One of the first bugs to be sequenced, H.pylori has a small genome (1.6 MD) befitting its lifestyle in a hostile acidic mucosal niche. Of the 1500 genes, 750-1000 are essential, the others are different in each strain. Hp has an "open pan-Genome" which means the more strains you look at the more genes you will find - i.e. you will never have a complete set of all its possible genes!
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Here is a good review about how we can take advantage of next-generation cheap and massive sequencing tech...
- Engstrand-2009-How will next-genera.pdf
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Here is an article you sent me about "The Sequence Factory" which is the BGI in Shenzen. I am using it to test the upload of a pdf less than 512 Kb.
Check the link below for information on hard-to-treat cases. Then search the forums for questions and answers similar to yours.